12:00-12:30 Venkata Satagopam, Unlocking complex diseases through federated data governance, FAIR multi-modal data, and AI

12:30-13:00 Vladimir Brusic, Monitoring heart health at home: Health informatics challenges

12:00-12:25 Verena Paulitschke, Noninvasive biomarker discovery by metabolomics of fingertip sweat to guide individualized anti-PD-1 immunotherapy in melanoma

12:25-12:40 Paula Stancl, Metaplasia as a transitional cell-of-origin state revealed by epigenome-informed cancer prediction

12:40-12:55 Luka Bojic, CTCF transcription factor as a potential therapeutic target in osteosarcoma

12:00-12:25 Jovana Kovacevic, Integration and standardization of gene–disease associations in ProDiGenIDB

12:25-12:40 Aleksandr Matsun, A pan-tissue multi-omics framework for aging analysis via non-negative matrix tri-factorization

12:40-12:55 Iva Rosić, EffRank: a bioinformatics scoring pipeline for prioritizing novel type III secreted effectors in the Pseudomonas syringae species complex

Finding Your Research Edge: From Cambridge to the Future of Life Sciences and AI

Lecturer: Stefan Milošević

This session is designed for students and young researchers who want to better understand how to build an international research path and find their own direction in the rapidly evolving field of life sciences and AI. Sharing firsthand insights from his own personal journey from Serbia to Cambridge, the lecturer will use his real-life experiences to deliver practical lessons on studying abroad, identifying a strong research fit, building confidence, and positioning yourself for future scientific trends such as computational biology, multi-omics, precision medicine, digital twins, and AI-driven biomedical innovation.

Exhibition Viewing

A dedicated session for participants to visit the exhibition area, engage with conference sponsors and industry partners, and explore the latest products, technologies, and services. It provides an excellent environment for networking, business development, and professional exchange.

Informal Poster Viewing

An open-ended session allowing participants to browse the poster presentations at their own pace. This slot is designed for independent viewing, casual discussions, and flexible networking among colleagues without formal presentation requirements.

14:00-14:30 Ágnes Tantos, Identifying regulatory RNA networks behind therapy-induced senescence (TIS) in breast cancer cells

14:30-15:00 Milana Grbić, Rethinking protein complex discovery from network topology to dynamic graph learning

15:00-15:05 Sandi Baressi Šegota, Confidence-guided lightweight CNN ensemble for OrganMNIST classification

15:05-15:10 Ross Stewart, Predicting interaction-specific protein–protein interaction perturbations by missense variants with MutPred-PPI

15:10-15:15 Marko Brkic, RefusalBench: Why refusal rate misranks frontier LLMs on biological research prompts

15:15-15:20 Natacha Cerisier, Predicting nephrotoxicity from cell morphological perturbations using high content image-based profiling

15:20-15:25 Milana Djonovic, Cross-workflow signal reporting in pan-viral metagenomics

15:25-15:30 Biljana Stojanović, Temporal dynamics of codon usage in SARS-CoV-2 proteins

15:35-15:40 Giulgaz Muradova, A compact genotype sketch for cross-platform sample matching

15:40-15:45 Anatoly Panov, Efficiency and resource potential of a pediatric palliative patronage model

15:45-15:50 Mikhail Potievskiy, Application of artificial intelligence–based digital medical technologies for the management of surgical patients with hepatopancreatobiliary tumors

As part of this special symposium, participants will explore the complete spatial transcriptomics workflow, from experimental planning and data generation to state-of-the-art bioinformatics analysis, gaining practical insights into one of the most transformative technologies in modern biology.

Speakers:
Aleksandra Divac Rankov, Institute of Molecular Genetics and Genetic Engineering, University of Belgrade
Nevena Vezmar, Institute of Molecular Genetics and Genetic Engineering, University of Belgrade
Igor Davidovic, Institute of Molecular Genetics and Genetic Engineering, University of Belgrade
Mateja Ilic, Institute of Molecular Genetics and Genetic Engineering, University of Belgrade

14:00-14:25 Yulia Medvedeva, Genetic and phenotypic heterogeneity of type 2 diabetes across Russian ancestry groups

14:25-14:50 Vladimir Jovanović, Dissecting the transcriptomic basis of behavioural differences between male morphs of ruffs (Calidris pugnax)

14:50-15:05 Anastasija Bubanja, Cell-type specific expression and structural features of transcriptional isoform LDLRAD4-217 in rectal cancer

15:05-15:20 Mehmet Izmirli, Omics-driven agent-based modelling of hepatocellular carcinoma tumours

15:20-15:35 Anja Petrović, Exploring the role of the ZBTB14 transcription factor in U937 macrophages

15:35-15:50 Alexander Rakitko, Genetic architecture and AI-assisted phenotyping of alopecia in a large Russian genomics cohort

BIO4 Partner Spotlight: EPAM Systems

As part of the BIO4 programme at BelBi, EPAM Systems will present Ketcher, a leading open-source platform for drawing, editing, and managing chemical structures and reactions. Attendees will have the opportunity to explore how modern digital technologies are accelerating scientific discovery and supporting research across biotechnology, drug discovery, computational chemistry, and the life sciences.

Exhibition Viewing

A dedicated session for participants to visit the exhibition area, engage with conference sponsors and industry partners, and explore the latest products, technologies, and services. It provides an excellent environment for networking, business development, and professional exchange.

Informal Poster Viewing

An open-ended session allowing participants to browse the poster presentations at their own pace. This slot is designed for independent viewing, casual discussions, and flexible networking among colleagues without formal presentation requirements.

10:00-10:25 Olga Tarasova, AI/ML in the search for novel antivirals

10:25-10:50 Marija Gavrović-Jankulović, Predictive modeling of B- and T-cell epitopes in allergen discovery and immunotherapy design

10:50-11:05 Uxia Veleiro, Predicting drug synergy under realistic scenarios

11:05-11:20 Branislava Jankovic, Targeting resistance and survival mechanisms in Pseudomonas aeruginosa using data fusion and machine learning

10:00-10:25 Andrey Przhibelskiy, A universal toolkit for single-cell and spatial long-read transcriptomic sequencing data

10:25-10:40 Alla Mikheenko, IsoChecker: multisample analysis and interactive browsing of long-read transcript isoforms

10:40-10:55 Milovan Suvakov, Detection of mosaic copy number alterations in PTA-amplified single cells

10:55-11:10 Igor Davidović, Improving spatial transcriptomics data processing and annotation under suboptimal image-based cell segmentation

BIO4 Partner Spotlight: EPAM Systems

As part of the BIO4 programme at BelBi, EPAM Systems will present Ketcher, a leading open-source platform for drawing, editing, and managing chemical structures and reactions. Attendees will have the opportunity to explore how modern digital technologies are accelerating scientific discovery and supporting research across biotechnology, drug discovery, computational chemistry, and the life sciences.

Exhibition Viewing

A dedicated session for participants to visit the exhibition area, engage with conference sponsors and industry partners, and explore the latest products, technologies, and services. It provides an excellent environment for networking, business development, and professional exchange.

Informal Poster Viewing

An open-ended session allowing participants to browse the poster presentations at their own pace. This slot is designed for independent viewing, casual discussions, and flexible networking among colleagues without formal presentation requirements.

Screen1

12:00-12:15 Nadja Trklja, Transcriptomic reanalysis reveals membrane-associated pathways involved in fullerenol C60(OH)24 cytotoxicity

12:15-12:30 Vanja Miljanić, Double-stranded RNA sequencing and bioinformatic analysis reveal viruses in Verticillium dahliae

12:30-12:45 Suzana Stanisavljević, Contribution of ILCs to the development of different forms of multiple sclerosis

12:45-13:00 Katarina Krstajić, Comprehensive genomic profiling of advanced Non-small Cell Lung Cancer in Serbia: Implications for targeted therapy selection

Screen2

12:00-12:15 Dragana Dudić, Assessing the predictive power of intrinsic disorder and sequence features for plant stress response

12:15-12:30 Katja Jamnik, Integrated analysis reveals bias in single-tool miRNA profiling during grapevine viral coinfection

12:30-12:45 Vladimir Vlatković, Assessment of coumarin derivatives potential as cyclooxygenase-2 inhibitors

12:45-13:00 Mateja Ilić, Spatial transcriptomic profiling of thrombin-PAR-fibrinogen axis in colorectal cancer

Screen3

12:00-12:15 Jelena Kusic-Tisma, Spatial organization of gene expression in 3-day old zebrafish larvae

12:15-12:30 Marija Lazić, Prothrombin reshapes the temporal transcriptomic trajectory of Caco-2 colorectal cancer cells

12:30-12:45 Marina Jelovac, Benchmarking of pre-processing steps in Sarek pipeline on MGI sequenced standard human genome

12:45-13:00 Nikita Yolshin, Genome-wide analysis of human respiratory adenoviruses in Russia reveals extensive diversity and recombination

Screen4

12:00-12:15 Sanja Goč, Bioinformatics identification of extracellular vesicle – derived microRNAs biomarkers in pancreatic cancer

12:15-12:30 Kristina Kokotović, Dynamics in soil microbial community structure under the influence of heavy metal contamination and phytoremediation: a pot trial experiment

12:30-12:45 Radmila Novakovic, Integrated chemical and metagenomic profiling of urban wastewater: antibiotic residues, microbial community and resistome at a Belgrade collector point

12:45-13:00 Marko Antonijević, Coordination geometry-driven selectivity toward tumor-associated carbonic anhydrases in novel Zn(II) dithiocarbamato complexes

Screen5

12:00-12:15 Manja Božić, Trehalose synthesis is induced in maize roots under low-temperature stress

12:15-12:30 Djordje Pavlovic, Implementation and clinical utility of the GATK gCNV pipeline for rare disease diagnostics using whole exome sequencing

12:30-12:45 Nikita Yolshin, Development of the amplification strategy and NGS data processing pipeline for HIV-1 genome assembly and resistance genotyping

12:45-13:00 Vanja Tatić, In silico approach to proteomic identification of biologically active proteins in an insect non-model species, Ostrinia nubilalis

Screen6

12:00-12:15 Vladimir Vlatković, Molecular docking approach in prediction of binding between selected bioactive phenolic compounds and human serum albumin

12:15-12:30 Natasa Radakovic, Transcriptomic analysis reveals suppression of the filamentation-associated virulence program in Candida albicans

12:30-12:45 Aleksandar Bisenić, Pilosibacter species emerge as leading contributors to glutarate pathway-mediated butyrate synthesis in the human gut

12:45-13:00 Jelena Pantović, Microbial composition of peloids from Banja Koviljača

12:00-12:25 Dušan Radojević, Gut microbiota profiling as a tool for predicting and enhancing immunotherapy response

12:25-12:40 Aleksandra Denisova, Meta-analysis of oral shotgun metagenomes for prediction of caries and periodontitis

12:40-12:55 Alina Guliaeva, Permafrost-preserved Late Pleistocene wolf from Yakutia: palaeogenomic and metagenomic perspectives

Blockchain Technologies: From Digital Trust to Real-World Impact

Lecturer: Strahinja Vukoičić

This session offers an engaging introduction to blockchain technology and its evolving role in building trust, transparency, and security in the digital world. Through real-world examples across different sectors, participants will explore how decentralized systems are transforming the way data is shared, verified, and managed. The session will also highlight key opportunities, current limitations, and future directions of blockchain-based systems in an increasingly connected digital ecosystem.

Exhibition Viewing

A dedicated session for participants to visit the exhibition area, engage with conference sponsors and industry partners, and explore the latest products, technologies, and services. It provides an excellent environment for networking, business development, and professional exchange.

Informal Poster Viewing

An open-ended session allowing participants to browse the poster presentations at their own pace. This slot is designed for independent viewing, casual discussions, and flexible networking among colleagues without formal presentation requirements.

14:00-14:30 Ming Chen, AI-driven bioinformatics: advancing chronic disease management and aging assessment

14:30-15:00 Noël Malod-Dognin, Exploiting the linearity of joint embedding spaces to mine cancer precision medicine knowledge

Screen1

15:00-15:15 Kirill Ulianov, Long-range chromatin interaction dynamics and molecular aging signatures in schizophrenia

15:15-15:30 Aleksandar Milovanović, Refining FFR assessment for gray zone coronary lesions

15:30-15:45 Sofia Dmitrienko, Contamination of the Toxoplasma gondii reference genome and an algorithm for its detection in paleometagenomic analysis

15:45-16:00 Anđela Damnjanović, Classification of coronavirus types based on repeats derived from amino acid and nucleotide sequences

Screen2

15:00-15:15 Jovana Stankic, AI‑driven concordance engines as a decision-support layer for veterinary import compliance

15:15-15:30 Jasmina Obradovic, Sex-specific distribution of EGFR rs712829 and rs712830 polymorphisms in East Asian, European and Serbian populations

15:30-15:45 Anastasia Matlaeva, PromoterLab: browser-based application for human promoter design, visualization and sequence analysis

15:45-16:00 Mirjana Novković, Identification of shared molecular programs and putative role of ankrd1a in zebrafish heart regeneration and skeletal muscle repair using WGCNA

Screen3

15:00-15:15 Kübra Tuğtekin, Comparative evaluation of the regenerative efficacy of Lucilia sericata larval secretions across varied storage conditions.

15:15-15:30 Jelena Karanović, Regulatory landscape of TGFB pathway in gastrointestinal tumors

15:30-15:45 Nikola Jocic, Development and validation of a reproducible RNA-seq pipeline for transcriptomic analysis

15:45-16:00 Miloš Nenadović, IntelliLung: A human-in-the-loop AI-DSS for ICU ventilation settings

Screen4

15:00-15:15 Nevena Ćirić, Hierarchical deep learning for tandem repeat proteins classification

15:15-15:30 Milana Grbić, Towards protein complex identification in dynamic PPI networks using embeddings

15:30-15:45 Sara Stankovic, Precision and recall in rare disease genomics: benchmarking the IMGGE whole genome sequencing pipeline

15:45-16:00 Filip Božić, Sequence diversity and genomic relatedness of blaVIM-positive clinical Proteus mirabilis isolates

Screen5

15:00-15:15 Bojana Banovic Deri, Multi-resolution framework for orthology and regulatory region delineation in divergent grass genomes

15:15-15:30 Janko Diminic, DigestedProteinDB: A compact key–value database for in silico peptide digestion and mass-based search

15:30-15:45 burak ozyurek, FluxInside: A high-performance Flux Balance Analysis engine for spatial agent-based models.

A unique networking event bringing together representatives of multiple European COST Actions to exchange ideas, build new connections, and explore shared scientific interests in bioinformatics, computational biology, multi-omics, and translational biomedicine.

14:00-14:10 Biljana Stankovic Introduction to COST Action Key Principles

14:10-14:25 Andrea Gelemanovic CA24166: Pan-European Network for Inflammaging: A Multi-omics Integration Approach (INFLAMomx)

14:25-14:40 Miron Sopic CA21153: Network for implementing multiomic approaches in atherosclerotic cardiovascular disease prevention and research (AtheroNET)

14:40-14:55 Ivana Stojanovic CA24117 – Innate lymphoid cells – the European quest for innovative cancer prognosis and immunotherapy (ILCquest)

14:55-15:10 Riste Stojanov CA24162 – Adaptive and acquired resistance in gastrointestinal cancers-contemporary and emerging resolutions (AdResCanCER)

15:10-15:20 Short brake

15:20-16:00 Discussion and networking

Exhibition Viewing

A dedicated session for participants to visit the exhibition area, engage with conference sponsors and industry partners, and explore the latest products, technologies, and services. It provides an excellent environment for networking, business development, and professional exchange.

Informal Poster Viewing

An open-ended session allowing participants to browse the poster presentations at their own pace. This slot is designed for independent viewing, casual discussions, and flexible networking among colleagues without formal presentation requirements.

10:00-10:30 Thomas Mohr, From fatty liver to scar: Exploring the rewiring of gene networks across the human chronic liver disease continuum.

10:30-11:00 Vladimir Kovacevic, Unraveling the molecular effects of nanoplastics on human blood cells using microfluidic chip-based single-cell RNA sequencing

11:00-11:15 Dušan Ušjak, An integrated single-nucleus landscape of cardiovascular disease

10:00-10:25 Gábor Erdős, Zero-shot prediction of thermodynamic properties of proteins

10:25-10:50 R. Gonzalo Parra, The role of local energetic frustration across conformational ensembles of disordered proteins

10:50-11:05 Norbert Deutsch, Pathogenic variations illuminate functional constraints in intrinsically disordered proteins

11:05-11:20 Pavle Goldstein, A statistical perspective on the Last Universal Common Ancestor (LUCA)

Exhibition Viewing

A dedicated session for participants to visit the exhibition area, engage with conference sponsors and industry partners, and explore the latest products, technologies, and services. It provides an excellent environment for networking, business development, and professional exchange.

Informal Poster Viewing

An open-ended session allowing participants to browse the poster presentations at their own pace. This slot is designed for independent viewing, casual discussions, and flexible networking among colleagues without formal presentation requirements.

12:00-12:25 Andrea Gelemanović, Multi-omics integration approaches for addressing cardio-renal-metabolic multimorbidity

12:25-12:40 Tarmo Nurmi, Deeply phenotyped and multi-omics data integration with the Human Phenotype Project

12:40-12:55 Milica Pajović, Integrated transcriptomic analysis reveals coordinated network reprogramming and p53 pathway inactivation in temozolomide-resistant gioblastoma A172 cell line

12:00-12:25 Minja Belic, Context-dependent remodeling of aging-related and neurodevelopmental pathways in human cerebral organoids across APOE genotypes

12:25-12:40 Cyril Lagger, Mechanistic insights into ageing biology from single-cell omics

12:40-12:55 Aleksandra Beric, Study of circulating blood linear RNA nominates CD55 and DLD as novel causal genes and early-stage biomarkers for Parkinson’s disease

Exhibition Viewing

A dedicated session for participants to visit the exhibition area, engage with conference sponsors and industry partners, and explore the latest products, technologies, and services. It provides an excellent environment for networking, business development, and professional exchange.

Informal Poster Viewing

An open-ended session allowing participants to browse the poster presentations at their own pace. This slot is designed for independent viewing, casual discussions, and flexible networking among colleagues without formal presentation requirements.

14:00-14:25 Predrag Radivojac, Resolving variants of uncertain significance at scale with calibrated computational and experimental evidence

14:25-14:40 Fedor Konovalov, A Bayesian framework for quantifying allele count evidence for variant pathogenicity

14:40-14:55 Yury Barbitoff, Understanding the interplay between positive and negative selection in the human genome

15:00-15:05 Nikola Kotur, Cytokine profiles as promising predictive biomarkers for glucocorticoid therapy response in inflammatory bowel disease

15:05-15:10 Tatjana Ruskovska, Integrative multi-layer bioinformatics of transcriptomic data for elucidating molecular mechanisms of action of polyphenol-rich extract on cardiometabolic health

15:10-15:15 Stefan Lazic, Cobalt chloride affects neural precursor cell differentiation: A transcriptional study

15:15-15:20 Mikhail Potievskiy, Cancer origin: Studying natural history of oncosupression under selection pressure

15:20-15:25 Biljana Stankovic, Rare variant pharmacogenomic analysis identifies pathways associated with vedolizumab response in Crohn’s disease patients

15:25-15:30 Kseniia Poliakova, Diet reconstruction of a woolly mammoth calf using multiple metagenomic approaches

15:30-15:35 Antonio Starcevic, A multi-omic digital twin network reveals C3-glycosylation as an actionable driver of latent metaflammation

15:35-15:40 Zorana Dobrijevic, Identification and functional characterization of tumor-suppresive microRNAs with potential key roles in breast cancer progression and metastasis

15:40-15:45 Nađa Trklja, Analysis of total transcriptome from brain tissue of progressive multiple sclerosis patients identifies ferroptosis-related genes relevant for distinction of inactive from chronic active white mater lesions

15:45-15:50 Cong Feng, CellAnalyst: delivering single-cell transcriptomic insights from bioinformatics analysts to experimental biologists

14:00-14:25 Lubomir Lou Chitkushev, Cyberbiosecurity threats in the time of AI: Digital vulnerabilities with biological consequences

14:25-14:50 Mikel Hernaez, Towards causal and interpretable virtual cells

14:50-15:05 Aleksandra Galitsyna, Generalized discovery of chromatin structural patterns across developmental and evolutionary scales

15:05-15:20 Ivan Lorencin, Structured generative AI for interpretable analysis of complex biomedical data

15:20-15:35 Mihailo Jovanovic, CardioSafe: Multi-task prediction of cardiac ion channel activity with reverse-leak audited benchmarking

15:35-15-50 Bogdan Kirillov, Time- and cost-efficient parameter optimization for 3D bioprinting of composite bioinks via active machine learning with Gaussian Processes

14:00-14:20 Fu-Sung Kim-Benjamin Tang, Federated learning in Healthcare across Europe: Challenges and Insights from the BETTER Project
14:20-14:40 Olgica Djurkovic-Djakovic, Framework for Clinical Trial Participants’ Data Reutilization – experience from the FACILITATE Project
14:40-15.00 Zaharije Radivojevic, Developing Trusted AI Ecosystems: the SAIFA Project Approach

Responsible Secondary Use of Health Data in Research

The panel will tackle questions about the value of secondary use of health data in research and various approaches related to data sharing. What are institution/country policies across Europe? How do we approach data security and patient consents? What are the use cases for secondary use of data? What is multi-omics data, how do we integrate data from different sources and how it can be used in research?
Moderator: Branislava Gemović, Centre for the Fourth Industrial Revolution in Serbia, Office for IT and eGovernment & Vinča Institute of Nuclear Sciences, University of Belgrade, Serbia

Panelists:

Maja Stojiljković, Institute of Molecular Genetics and Genetic Engineering, University of Belgrade, Serbia

Paula Štancl, Faculty of Science, University of Zagreb, Croatia

Vladimir Jovanović, Institute of Biology, Freie Universität Berlin, Germany

Zaharije Radivojević, School of Electrical Engineering, University of Belgrade, Serbia

Exhibition Viewing

A dedicated session for participants to visit the exhibition area, engage with conference sponsors and industry partners, and explore the latest products, technologies, and services. It provides an excellent environment for networking, business development, and professional exchange.

Informal Poster Viewing

An open-ended session allowing participants to browse the poster presentations at their own pace. This slot is designed for independent viewing, casual discussions, and flexible networking among colleagues without formal presentation requirements.